Elements of Molecular Neurobiology by C. U. M. Smith

Product Description

This edition of the popular text incorporates recent advances in neurobiology enabled by modern molecular biology techniques. Understanding how the brain works from a molecular level allows research to better understand behaviours, cognition, and neuropathologies. Since the appearance six years ago of the second edition, much more has been learned about the molecular biology of development and its relations with early evolution. This "evodevo" (as it has come to be known) framework also has a great deal of bearing on our understanding of neuropathologies as dysfunction of early onset genes can cause neurodegeneration in later life. Advances in our understanding of the genomes and proteomes of a number of organisms also greatly influence our understanding of neurobiology.
* Well known and widely used as a text throughout the UK, good reviews from students and lecturers.
* Good complement to Fundementals of Psychopharmacology by Brian Leonard.
This book will be of particular interest to biomedical undergraduates undertaking a neuroscience unit, neuroscience postgraduates, physiologists, pharmacologists.
It is also a useful basic reference for university libraries.
Maurice Elphick, Queen Mary, University of London
"I do like this book and it is the recommended textbook for my course in Molecular Neuroscience. The major strength of the book is the overall simplicity of the format both in terms of layout and diagrams."
Product Details

* Amazon Sales Rank: #501745 in Books
* Published on: 2002-11-15
* Number of items: 1
* Binding: Paperback
* 630 pages

Editorial Reviews

Review
"…will prove very useful to every individual interested in molecular neurobiology research..." (Journal of Chemical Neuroanatomy, Vol.29, 2005)

Download Description
This thoroughly revised and updated new edition of C.U.M. Smith's 1996 text gives an account of the molecular biology of the brain as it stands at the beginning of the twenty-first century. While retaining the overall structure of the second edition, this new edition incorporates new material on: genomics; ion channels; neural stem cells; gap junctions; channelopathies; cannabinoids; DNA-chips manipulation of K+-channels; molecular bases of memory; motor neuron disease; Alzheimer's Disease.

Book Info
Aston Univ., Birmingham, UK. Comprehensive updated textbook gives an account of the molecular biology of the brain. Contains new topics on genomics, ion channels, neural stem cells, gap-junctions, channelopathies, cannabinoids, DNA-chips and molecular bases of memory. Softcover, hardcover available, listed in approval week 2003-12. Previous edition: c1989.

Dangerous Harvest: Drug Plants and the Transformation of Indigenous Landscapes

Product Description

The global drug trade and its associated violence, corruption, and human suffering create global problems that include political and military conflicts, ethnic minority human rights violations, and stresses on economic development. Drug production and eradication affects the stability of many
states, shaping and sometimes distorting their foreign policies. External demand for drugs has transformed many indigenous cultures from using local agricultural activity to being enmeshed in complex global problems.

Dangerous Harvest presents a global overview of indigenous peoples' relations with drugs. It presents case studies from various cultural landscapes that are involved in drug plant production, trade, and use, and examines historical uses of illicit plant substances. It continues with coverage of
eradication efforts, and the environmental impact of drug plant production. In its final chapter, it synthesizes the major points made and forecasts future directions of crop substitution programs, international eradication efforts, and changes in indigenous landscapes. The book helps unveil the
farmer, not to glamorize those who grow drug plants but to show the deep historical, cultural, and economic ties between farmer and crop.

Product Details
Amazon Sales Rank: #1545286 in Books
Published on: 2004-04-01
Number of items: 1
Binding: Paperback
336 pages
Editorial Reviews

Review
"This volume is readable, entertaining, and thought-provoking throughout..."The Professional Geographer

"Informative and well written...the reader cannot help but be impressed by what a powerful influence the international drug trade has had on international relations, political and military struggles, environmental health and security, and economic well-being in many contexts."--The Geographic Review

About the Author
Michael K. Steinberg is Adjunct Professor of Geography at Louisiana State University and Cultural Biogeographer with the U.S.D.A.'s National Plant Data Center. Dr. Steinberg specializes in cultural and political ecology of indigenous peoples in Central America. His research has appeared in journals such as Geographical Review, Economic Botany, and The Professional Geographer. He is also the editor of Cultural and Physical Expositions, Geographical Studies in the Southern United States and Latin America, published by Geoscience Publications, and Forests, Fields, and Fish: Politicized Indigenous Landscapes. He received his Ph.D. from Louisiana State University in geography in 1999.

Calcium-Binding Protein Protocols: Volume 1: Reviews and Case Histories (Methods in Molecular Biology)

Product Description

Blurb for Volume 1

Hans Vogel and a panel of leading researchers review the protein chemistry and behavior of this significant protein class, and provide a comprehensive collection of proven experimental techniques for their study both in vitro and in vivo. This first volume discusses the role of calcium in intracellular secondary messenger activation mechanisms, including unique aspects of calcium chemistry and its utilization in diary proteins and blood clotting. Detailed case studies provide a wealth of valuable information about protein purification and characterization strategies, X-ray crystallography, and specific calcium-binding proteins and their modes of action. The second companion volume focuses on cutting-edge experimental methods for studying solution structure, stability, dynamics, calcium-binding properties, and biological activity of calcium-binding proteins in general.

Single Blurb for Both Volumes:
Hans Vogel and a panel of leading researchers review the protein chemistry and behavior of this significant protein class, and provide a comprehensive collection of proven experimental techniques for their study both in vitro and in vivo. The first volume discusses the role of calcium in intracellular secondary messenger activation mechanisms, including unique aspects of calcium chemistry and its utilization in dairy proteins and blood clotting. Detailed case studies provide a wealth of valuable information about protein purification and characterization strategies, X-ray crystallography, and specific calcium-binding proteins and their modes of action. The second volume focuses on cutting-edge experimental techniques for studying the solution structure, stability, dynamics, calcium-binding properties, and biological activity of calcium-binding protein in general. In addition to enzymatic assays and more routine spectroscopic and protein chemistry techniques, there are also NMR approaches, thermodynamic analyses, kinetic measurements such as surface plasmon resonance, strategies for amino acid sequence alignments, and fluorescence methods to study the distribution of calcium and calcium-binding proteins in cells.

Product Details
Amazon Sales Rank: #3184480 in Books
Published on: 2001-12-15
Number of items: 1
Binding: Hardcover
360 pages
Editorial Reviews

Book Info
Univ. of Calgary, Alberta, Canada. Features all major biophysical and protein methods to study calcium-binding proteins and includes a detailed discussion of calcium-binding proteins in vitro and in vivo. Many of the methods are also applicable to proteins not binding to calcium.