Osteoarthritic Joint Pain

Product Description

Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the quality of life in affected individuals. The major symptoms are chronic pain, swelling and stiffness; severe, chronic joint pain is often the central factor that causes patients to seek medical attention. Within the affected joint, there is focal degradation and remodelling of articular cartilage, new bone formation (osteophytes) and mild synovitis.

Several mechanisms are thought to contribute to osteoarthritic joint pain. These include mild synovial inflammation, bone oedema, ligament stretching, osteophyte formation and cartilage-derived mediators. Changes in joint biomechanics and muscle strength also influence the severity and duration of joint pain in osteoarthritis. Within the nervous system, the relative contributions of peripheral afferent nociceptive fibres and central mechanisms remain to be defined, and there is limited information on the phenotype of sensory neurons in the OA joint. Importantly, there is no relation between clinical severity, as measured by radiographic changes, and the presence and severity of joint pain. Patients with severe joint pain may have normal joint architecture as determined by X-ray, whereas patients with considerable evidence of joint remodelling may not have significant joint pain. Treatments for osteoarthritic joint pain include non-steroidal anti-inflammatory compounds, exercise, corrective shoes and surgical intervention. There remains a critical need for improved control of joint pain in osteoarthritis.

This book brings together contributions from key investigators in the area of osteoarthritic joint pain. It covers the clinical presentation of joint pain, the pathways involved in joint pain, osteoarthritis disease processes and pain, experimental models and pain control. The discussions provide insights into the nature of osteoarthritic joint pain, identify key studies needed to advance understanding of the problem, highlight possible intervention points and indicate future pathways towards a better treatment of osteoarthritic joint pain.
Product Details

* Amazon Sales Rank: #740837 in Books
* Published on: 2004-06-25
* Original language: English
* Number of items: 1
* Binding: Hardcover
* 302 pages

Editorial Reviews

Download Description
Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the quality of life in affected individuals. The major symptoms are chronic pain, swelling and stiffness; severe, chronic joint pain is often the central factor that causes patients to seek medical attention. Within the affected joint, there is focal degradation and remodelling of articular cartilage, new bone formation (osteophytes) and mild synovitis.

Several mechanisms are thought to contribute to osteoarthritic joint pain. These include mild synovial inflammation, bone oedema, ligament stretching, osteophyte formation and cartilage-derived mediators. Changes in joint biomechanics and muscle strength also influence the severity and duration of joint pain in osteoarthritis. Within the nervous system, the relative contributions of peripheral afferent nociceptive fibres and central mechanisms remain to be defined, and there is limited information on the phenotype of sensory neurons in the OA joint. Importantly, there is no relation between clinical severity, as measured by radiographic changes, and the presence and severity of joint pain. Patients with severe joint pain may have normal joint architecture as determined by X-ray, whereas patients with considerable evidence of joint remodelling may not have significant joint pain. Treatments for osteoarthritic joint pain include non-steroidal anti-inflammatory compounds, exercise, corrective shoes and surgical intervention. There remains a critical need for improved control of joint pain in osteoarthritis.

This book brings together contributions from key investigators in the area of osteoarthritic joint pain. It covers the clinical presentation of joint pain, the pathways involved in joint pain, osteoarthritis disease processes and pain, experimental models and pain control. The discussions provide insights into the nature of osteoarthritic joint pain, identify key studies needed to advance understanding of the problem, highlight possible intervention points and indicate future pathways towards a better treatment of osteoarthritic joint pain.

From the Back Cover
Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of four in every 100 people and significantly reduces the quality of life in affected individuals. The major symptoms are chronic joint pain, swelling and stiffness; severe pain is often the key factor causing patients to seek medical attention. Within the affected joint there is focal degradation and remodelling of articular cartilage, new bone formation and mild synovitis.

Several mechanisms are thought to contribute to osteoarthritic joint pain, including mild synovial inflammation, bone oedema, ligament stretching, osteophyte formation and cartilage-derived mediators. Changes in joint biomechanics and muscle strength may also affect the severity and duration of the joint pain. From a nervous system perspective, the relative contributions of peripheral afferent nociceptive fibres and central mechanisms remain to be defined. Importantly, there is a clear disconnect between clinical severity, as measured radiographically, and the presence and severity of joint pain. Treatments for osteoarthritic joint pain include non-steroidal anti-inflammatory compounds, exercise and surgical intervention. There remains a critical need for improved control of joint pain in osteoarthritis.

This book covers the clinical presentation of joint pain, the cellular pathways involved, osteoarthritis disease processes and pain, experimental models and pain control. The discussions provide insights into the nature of joint pain, identify key studies needed to advance understanding, highlight possible intervention points and indicate opportunities for better treatment of OA joint pain.

Pain Research: Methods and Protocols

Product Description

A cutting-edge collection of diverse readily reproducible techniques for dissecting the molecular mechanisms of pain transduction. These methods employ a variety of multidisciplinary approaches ranging from animal pain models and single neutron selection to in vitro single-cell mRNA amplification. The collection includes not only standard and cutting-edge methods, but also novel techniques only recently applied to pain research. The protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Product Details

* Amazon Sales Rank: #1595088 in Books
* Published on: 2004-05-15
* Original language: English
* Number of items: 1
* Binding: Hardcover
* 320 pages

Editorial Reviews

Book Info
Univ. of California, Orange. Describes in step-by-step detail diverse and novel techniques for dissecting the molecular mechanisms of pain transduction. Offers reproducible methods to study pain transduction for researchers. DNLM: Pain-physiopathology--Laboratory Manuals.

Perioperative Critical Care Cardiology (Topics in Anaesthesia and Critical Care)

Product Description


In this book are discussed topics of particular importance to critical care cardiovascular diagnosis and management in the perioperative period. Chapter topics are the causes for heart failure; the pathophysiology of heart failure; coronary heart disease and ischemic preconditioning; hypertensive urgencies and emergencies; diagnosis of heart failure; preoperative cardiac risk assessment; hemodynamic monitoring in patients with heart failure; electrocardiography of heart failure - features and arrhythmias; pharmacologic management for patients with heart failure; devices for management of heart failure; pacemaker and internal cardioverter-defibrillator therapies; management of cardiopulmonary arrest; circulatory shock - anaphylactic, cardiogenic, haemorrhagic, septic; prevention and management of cardiac dysfunction during and after cardiac surgery; vasodilator therapy - systemic and pulmonary; and, thromboembolism and anticoagulation. This work represents an important update for anaesthesiologists, cardiologists, cardiac surgeons, emergency care physicians and intensivists caring for patients with acute, life-threatening cardiovascular afflictions.
Product Details
Amazon Sales Rank: #1417956 in Books
Published on: 2007-02-02
Number of items: 1
Binding: Paperback
282 pages
Editorial Reviews

Book Info
Univ. of Wisconsin, Milwaukee. Update for cardiologists, anesthesiologists, cardiac surgeons, and intensivists. Different aspects of cardiovascular dysfunction are presented, including diagnosis, monitoring, and treatment in the perioperative period. Softcover.

Vital Signs and Resuscitation (Vademecum) by Joseph V. Stewart

Product Details
Amazon Sales Rank: #2414162 in Books
Published on: 2003-06
Number of items: 1
Binding: Spiral-bound
167 pages
Editorial Reviews

Book Info
Chicago Medical School, IL. Pocket-sized text provides the procedures for taking accurate vital signs. Provides an historical overview and covers such vital signs as temperature, heart rate, respiration, blood pressure, and level of consciousness. For nurses, residents and physicians. Wire-spiral binding. DNLM: Physical Examination--methods.

Handbook of Pain Assessment, Second Edition From The Guilford Press

Product Details

* Amazon Sales Rank: #191289 in Books
* Published on: 2001-07-10
* Number of items: 1
* Binding: Hardcover
* 798 pages

Editorial Reviews

Review
"The authoritative text on the assessment of patients with chronic pain has been updated and made even more useful. Researchers and clinicians will find this book a dependable and thorough review of pain measurement, behavioral assessment, medical and psychological evaluation, and outcomes studies. No single book does a better job on these topics. This book belongs in the library of all those who provide care to or undertake research on patients with chronic pain."--John D. Loeser, MD, Department of Neurological Surgery, University of Washington

"This is a remarkably scholarly yet readable volume. The internationally known authors provide in-depth explanations of the basic issues and balanced discussions of the controversial ones. The diversity and breadth of coverage make this book superior to many much larger texts. It accomplishes the critically important task of teaching assessment of both the diseases that cause pain and the persons who suffer from pain. It will serve as a useful introductory text for medical students and graduate students in psychology, and as a source of broader knowledge for pain medicine practitioners whose strengths lie in particular disciplines."--Edward C. Covington, MD, Director, Chronic Pain Rehabilitation Program, Cleveland Clinic Foundation, Cleveland, Ohio

"Turk and Melzack have set out to provide a comprehensive review of pain assessment, and they have clearly achieved their goal. Chapter authors are authoritative, well-regarded clinicians and researchers, and their contributions are thought-provoking and concise, with surprisingly little overlap. The book not only covers time-honored theories, questions, and concerns, but also addresses contemporary issues brought about by new discovery and technology. A'must' for pain researchers and clinicians, this volume is also well-suited for classroom use."--Daniel M. Doleys, PhD, Director, Pain and Rehabilitation Institute at Montclair, Birmingham, AL


"This book should have included the words ¿Totally Comprehensive' in the title. It includes almost every known pain assessment methodology and their specific uses, values, limitations and drawbacks....This book is an excellent reference book not only for choosing which evaluation tools to use but also for teaching the nursing staff how to ask patients about their pain on a daily basis....this book should be on the bookshelf of anyone who treats patients with chronic pain, anyone who is called upon to assess patients for pain, and anyone who has to teach others how to properly monitor pain states. I would recommend that this book be available to all students, interns, and residents in training programs as a reference when they have patients with pain."--Psychosomatics

"A comprehensive text such as this will be extremely useful both for researchers and clinicians. All kinds of pain from headaches to back pain to cancer pain are discussed and assessment in different kinds of people such as children, the elderly, persons with limited communication, and couples and families are included. Researchers might use it to find new useful measurement instruments or review the latest research on these means of assessment. Clinicians from many specialties may find the book useful for learning more about assessing and understanding the pain their patients may be experiencing. This book is recommended for all kinds of medical libraries from clinical and hospital libraries to academic research libraries."--E-Streams

"...collects valuable information that would otherwise be scattered in the literature."--Psychotherapy and Psychosomatics

"...a comprehensive review of the state of the art of pain assessment....The editors are distinguished psychologists who have made major contributions to the literature on pain. Turk and Melzack have chosen an impressive roster of contributors....should be in every university and health centre library. All health professionals and students who see patients who have pain (and that is probably all of them) should have this text readily available."--Canadian Psychology

"The individual chapters are well written, thorough, and an excellent source of information. This volume will undoubtedly prove extremely useful to researchers in decision making concerning instruments to use for the assessment of pain and related variables (e.g., physical and psychological functioning, pain beliefs, and coping strategies) for particular purposes or with specific populations....also will be useful for clinicians of different specialties that wish to learn more about the assessment of patients with pain....Strengths in addition to the superb content are an attractive layout; useful tables, figures, and other illustrations; cross-references to other chapters that cover a specific topic; and author and subject indexes. All in all, this is an excellent book."--APS Bulletin (American Pain Society)

Review
"This book should have included the words ¿Totally Comprehensive' in the title. It includes almost every known pain assessment methodology and their specific uses, values, limitations and drawbacks....This book is an excellent reference book not only for choosing which evaluation tools to use but also for teaching the nursing staff how to ask patients about their pain on a daily basis....this book should be on the bookshelf of anyone who treats patients with chronic pain, anyone who is called upon to assess patients for pain, and anyone who has to teach others how to properly monitor pain states. I would recommend that this book be available to all students, interns, and residents in training programs as a reference when they have patients with pain."--Psychosomatics "A comprehensive text such as this will be extremely useful both for researchers and clinicians. All kinds of pain from headaches to back pain to cancer pain are discussed and assessment in different kinds of people such as children, the elderly, persons with limited communication, and couples and families are included. Researchers might use it to find new useful measurement instruments or review the latest research on these means of assessment. Clinicians from many specialties may find the book useful for learning more about assessing and understanding the pain their patients may be experiencing. This book is recommended for all kinds of medical libraries from clinical and hospital libraries to academic research libraries."--E-Streams "...collects valuable information that would otherwise be scattered in the literature."--Psychotherapy and Psychosomatics "...a comprehensive review of the state of the art of pain assessment....The editors are distinguished psychologists who have made major contributions to the literature on pain. Turk and Melzack have chosen an impressive roster of contributors....should be in every university and health centre library. All health professionals and students who see patients who have pain (and that is probably all of them) should have this text readily available."--Canadian Psychology "The individual chapters are well written, thorough, and an excellent source of information. This volume will undoubtedly prove extremely useful to researchers in decision making concerning instruments to use for the assessment of pain and related variables (e.g., physical and psychological functioning, pain beliefs, and coping strategies) for particular purposes or with specific populations....also will be useful for clinicians of different specialties that wish to learn more about the assessment of patients with pain....Strengths in addition to the superb content are an attractive layout; useful tables, figures, and other illustrations; cross-references to other chapters that cover a specific topic; and author and subject indexes. All in all, this is an excellent book."--APS Bulletin (American Pain Society)

Book Info
Univ. of Washington, Seattle. Six sections cover pain assessment, behavioral expressions of pain, diagnostic methods, psychiatric disorders in people with chronic pain, features of diagnosing and assessing patients with acute pain, and important topics transcending the topic of assessment. Previous edition: c1992.` DNLM: Pain--diagnosis.

Bringing Pain Relief to Children: Treatment Approaches From Humana Press

Product Description

A panel of prominent clinician-scientists comprehensively reviews the latest developments in pediatric pain management, with special emphasis on the setting in which pain is detected and managed. The authors explore the cutting-edge of children's pain care in inpatient, outpatient, palliative care, school, and residential settings, and describe alternate approaches, including complementary and alternative medicine, pain management via the internet and information technology, and pain care in developing countries.
Product Details
Amazon Sales Rank: #1858735 in Books
Published on: 2006-04-01
Number of items: 1
Binding: Hardcover
256 pages
Editorial Reviews

Review

"...a good source for physicians as well as other healtcare providers who may participate in the care of children in environments likely to cause discomfort." -Weighted Numerical Score: 91 - 4 Stars!-Doody's Health Science Book Review Journal


"...serves as an up-to-date review of contemporary approaches to the unique needs of pediatric patients." -Weighted Numerical Score: 91 - 4 Stars!-Doody's Health Science Book Review Journal

Perioperative Critical Care Cardiology (Topics in Anaesthesia and Critical Care) From Springer

Product Description


In this book are discussed topics of particular importance to critical care cardiovascular diagnosis and management in the perioperative period. Chapter topics are the causes for heart failure; the pathophysiology of heart failure; coronary heart disease and ischemic preconditioning; hypertensive urgencies and emergencies; diagnosis of heart failure; preoperative cardiac risk assessment; hemodynamic monitoring in patients with heart failure; electrocardiography of heart failure - features and arrhythmias; pharmacologic management for patients with heart failure; devices for management of heart failure; pacemaker and internal cardioverter-defibrillator therapies; management of cardiopulmonary arrest; circulatory shock - anaphylactic, cardiogenic, haemorrhagic, septic; prevention and management of cardiac dysfunction during and after cardiac surgery; vasodilator therapy - systemic and pulmonary; and, thromboembolism and anticoagulation. This work represents an important update for anaesthesiologists, cardiologists, cardiac surgeons, emergency care physicians and intensivists caring for patients with acute, life-threatening cardiovascular afflictions.
Product Details
Amazon Sales Rank: #1657770 in Books
Published on: 2007-02-02
Number of items: 1
Binding: Paperback
282 pages
Editorial Reviews

Book Info
Univ. of Wisconsin, Milwaukee. Update for cardiologists, anesthesiologists, cardiac surgeons, and intensivists. Different aspects of cardiovascular dysfunction are presented, including diagnosis, monitoring, and treatment in the perioperative period. Softcover.

Core Topics in Pain by Anita Holdcroft

Product Description

Core Topics in Pain provides a comprehensive, easy-to-read introduction to this multi-faceted topic, from the underlying neurobiology, through pain assessment (in animals and humans), diagnostic strategies, clinical presentations, pain syndromes, to the many treatment options (e.g. physical therapies, drug therapies, psychosocial care) and the evidence base for each of these. Written and edited by experts of international renown, the many concise but comprehensive chapters provide the reader with an up-to-date guide to all aspects of pain. It is an essential book for anaesthetic trainees and is also an invaluable first reference for surgical and nursing staff, ICU professionals, operating department practitioners, physiotherapists, psychologists, healthcare managers and researchers with a need for an overview of the key aspects of the topic.
Product Details

* Amazon Sales Rank: #1956790 in Books
* Published on: 2005-11-14
* Number of items: 1
* Binding: Hardcover
* 366 pages

Editorial Reviews

Download Description
Core Topics in Pain provides a comprehensive, easy-to-read introduction to this multi-faceted topic. It covers a wide range of issues from the underlying neurobiology, through pain assessment in animals and humans, diagnostic strategies, clinical presentations, pain syndromes, to the many treatment options, for example, physical therapies, drug therapies, psychosocial care and the evidence base for each of these. Written and edited by experts of international renown, the many concise but comprehensive chapters provide the reader with an up-to-date guide to all aspects of pain. It is an essential book for anaesthetic trainees and is also an invaluable first reference for surgical and nursing staff, ICU professionals, operating department practitioners, physiotherapists, psychologists, healthcare managers and researchers with a need for an overview of the key aspects of the topic.

Download Description
Core Topics in Pain provides a comprehensive, easy-to-read introduction to this multi-faceted topic. It covers a wide range of issues from the underlying neurobiology, through pain assessment in animals and humans, diagnostic strategies, clinical presentations, pain syndromes, to the many treatment options, for example, physical therapies, drug therapies, psychosocial care and the evidence base for each of these. Written and edited by experts of international renown, the many concise but comprehensive chapters provide the reader with an up-to-date guide to all aspects of pain. It is an essential book for anaesthetic trainees and is also an invaluable first reference for surgical and nursing staff, ICU professionals, operating department practitioners, physiotherapists, psychologists, healthcare managers and researchers with a need for an overview of the key aspects of the topic.