Principles of Clinical Pharmacology

Product Description

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists.

* Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy.
* Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course.
* Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study.
* Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry.
* Expanded coverage of pharmacogenetics
* Expanded coverage of drug transporters and their role in interactions
* Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions
* A new chapter on drug discovery that focuses on oncologic agents
* Inclusion of therapeutic antibodies in chapter on biotechnology products
Product Details

* Amazon Sales Rank: #400931 in Books
* Published on: 2006-10-04
* Original language: English
* Number of items: 1
* Binding: Hardcover
* 568 pages

Editorial Reviews

Review
"Recent advances in pharmacogenetics, membrane transport, and biotechnology warrant a second edition of this excellent book...This will serve as an excellent text for an advanced course in principles of clinical pharmacology for graduate students, physicians, and PharmDs. Because of recent advances, the second edition is welcome." - Thomas L. Pazdernik, PhD, University of Kansas Medical Center, FOR DOODY'S (4 Stars)

Review
"Recent advances in pharmacogenetics, membrane transport, and biotechnology warrant a second edition of this excellent book...This will serve as an excellent text for an advanced course in principles of clinical pharmacology for graduate students, physicians, and PharmDs. Because of recent advances, the second edition is welcome."
- Thomas L. Pazdernik, PhD, University of Kansas Medical Center, FOR DOODY'S (4 Stars)

From the Back Cover
The rate of introduction of new pharmaceutical products has increased rapidly over the past decade, and details learned about a particular drug become obsolete as it is replaced by newer agents. For this reason, this book focuses on the principles that underlie the clinical use and contemporary development of pharmaceuticals. The coverage of these principles that is presented in this book will be of particular benefit to individuals engaged either in the teaching or study of sound therapeutic technique or in the investigation of pharmacological agents.

New to the Second Edition

The Second Edition retains the goal, format, and presentation style of the first edition but has been extensively updated and revised with the inclusion of many new authors and co-authors. In addition the second edition features:

* Pharmacogenetics - Expanded coverage of pharmacogenetics.

* Expanded coverage of drug transporters and their role in interactions.

* New material added on enzyme induction mechanisms to the chapters on drug metabolism and drug interactions.

* New Chapter! - A new chapter on Drug Discovery has been added with a focus on oncologic agents.

* New coverage of therapeutic antibodies has been added to the chapter on biotechnology products.

Hallmark Features

* Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy.

* Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course.

* Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study.

* Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry.
Customer Reviews

Excellent resource for post-graduate training5
In my opinion, this is the best book on general principles without going into detail on specific therapeutic areas. I would consider it a must-read for those in clinical pharmacology post-graduate training or those working in clin pharm. However, previous knowledge of pharmacology is needed, as this book is not suitable as a first primer for medical and undergrad students.

Excellent resource for post graduate training!5
In my opinion, this is the best book I have come acrorss in terms of "PRINCIPLES" The book focuses on general principles, not specific therapeutic areas. Topics covered range from drug discovery and development to individualization and quality assessment of drug therapy. This is an excellent resource for those in post-graduate Clinical Pharmacology training or who are working in this area. Readers will,
however, need a basic knowledge of pharmacology as this book is not suitable as the first and only Clinical Pharmacology textbook for medical or undergraduate students.

Excellent resource for post graduate training!5
In my opinion, this is the best book I have come acrorss in terms of "PRINCIPLES" The book focuses on general principles, not specific therapeutic areas. Topics covered range from drug discovery and development to individualization and quality assessment of drug therapy. This is an excellent resource for those in post-graduate Clinical Pharmacology training or who are working in this area. Readers will,
however, need a basic knowledge of pharmacology as this book is not suitable as the first and only Clinical Pharmacology textbook for medical or undergraduate students.